Study links vascular injury, not amyloid deposition, to MCI

02/12/2013 | MedPage Today (free registration)

Vascular brain injury may be linked to mild cognitive impairment, but the accumulation of beta amyloid protein does not seem to be connected to MCI, according to a study published in JAMA Neurology. There was also no indication that vascular brain injury and the buildup of beta amyloid protein, conditions that often occur together, are inter-related, the study said. Researchers used MRI to identify infarcts and PET imaging with Pittsburgh Compound B to assess beta amyloid. "If there is an association between vascular risk and beta amyloid, it does not appear to be mediated by vascular brain injury," researchers said.

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