Blocking agents help overcome immune rejection of stem cells in mice

03/3/2011 | Google

Scientists at Stanford University reported in the journal Cell Stem Cell that they were able to overcome immune system rejection of transplanted embryonic stem cells in mice after administering a short-term treatment with three co-stimulatory receptor blocking agents, drugs that "teach" T cells to accept transplanted cells. The finding might allow patients to receive donor cells without requiring them to use immunosuppressive drugs and might help prevent transplanted early-stage cells from turning into tumors.

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