Patients who used diclofenac to relieve arthritis pain faced a 39% higher risk of heart attack and were 40% more likely to suffer cardiovascular events compared with people who did not use the drug. "When doctors prescribe [non-steroidal anti-inflammatory drugs], they need to consider the patient's risk profile. Particularly for patients with higher risk of cardiovascular events, a doctor should either advise against NSAID use or recommend one that has a relatively low cardiovascular risk," the researchers wrote in PLoS Medicine.
Diclofenac raises odds of cardiovascular events, study finds
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