The rate of abnormal stress-rest SPECT-MPI tests has declined from 40.9% in 1991 to 8.7% in 2009, according to a study published in the Journal of the American College of Cardiology. The researchers also observed a similar trend concerning ischemic results and moderately to severely abnormal findings. The study reviewed data on 39,515 patients at Cedars-Sinai Medical Center in Los Angeles. The results "may be reflecting a broader temporal change toward milder clinical presentations of coronary artery disease (CAD)," according to the researchers. They said the report "suggests a need to refine the future diagnostic workup of patients with suspected CAD."
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