T cell therapy shows promise against acute adult leukemia

03/21/2013 | New York Times (tiered subscription model), The

A cellular therapy has induced remission in a deadly form of adult acute leukemia, Memorial Sloan-Kettering Cancer Center researchers reported in the journal Science Translational Medicine. The therapy uses disabled viruses to program T cells to attack B cells, and it has been used to treat other forms of leukemia. "This is the first report showing some real, clinically beneficial activity in adult acute lymphoblastic leukemia," said Dr. Carl June of the University of Pennsylvania, who is developing a similar treatment.

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