PET imaging with 18F-florbetaben IDs Alzheimer's

04/2/2013 | MolecularImaging.net

Uptake of 18F-florbetaben on PET imaging scans was higher in the cerebral cortex of patients with Alzheimer's disease than in healthy study participants, according to a study published in the Journal of Nuclear Medicine. Researchers used a kinetic compartment theory of analysis for this study. "Compartment kinetic model-based quantification of [beta-amyloid] binding from 18F-florbetaben PET data is feasible, and all [beta-amyloid] binding parameters, including those by the reference tissue model and the practically useful SUVR, are excellent in discriminating between beta-amyloid–positive–and–negative scans," researchers said.

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