2 approved drugs show promise in treating prion disease

04/4/2013 | Yahoo

Researchers have found that two drugs already approved for use in humans -- tacrolimus and astemizole -- reduce the amount of prion protein present on cell surfaces by about 70%. Misfolded forms of the proteins are believed to cause such diseases as Creutzfeldt-Jakob disease. Astemizole is the most promising because it is effective at relatively low doses, while tacrolimus can cause neurotoxicity.

View Full Article in:

Yahoo

Published in Brief:

SmartBrief Job Listings for Health Care

Job Title Company Location
Associate Director, Compliance Business Partner I
Boehringer Ingelheim
Ridgefield, CT
European Sales Manager
SentreHEART, Inc.
Germany, Benelux, UK
REG AFFAIRS PROJ MGR - 1400000A7F
Abbott
San Jose, CA
SPECIALIST II SYSTEMS INTEGRATION - 140000033P
Abbott
Dallas, TX
Attorney
U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES Food and Drug Administration Office of the Chief Counsel
Silver Spring, MD, MD