Beta-cell autoimmunity affects gut microbes in children

04/7/2013 | PhysiciansBriefing.com

Children with beta-cell autoimmunity had reduced levels of lactate- and butyrate-producing gut bacteria, lower Bifidobacterium adolescentis and Bifidobacterium psuedocatenulatum rates and a higher amount of Bacteroides genus, a study indicated. More studies are needed as "low abundance of bifidobacteria and butyrate-producing species could adversely affect the intestinal epithelial barrier function and inflammation, whereas the apparent importance of the Bacteroides genus in development of type 1 diabetes is insufficiently understood," researchers wrote in Diabetes.

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