Researchers crack the complex workings of CuAAC reaction

04/10/2013 | Chemical & Engineering News

Researchers have found a potential mechanism for the Cu(I)-catalyzed azide-alkyne cycloaddition reaction, and the findings explain "how metals interact with carbon-carbon multiple bonds," said lead researcher Valery Fokin. "This is the first time someone was able to show there is a two-copper intermediate that is very short-lived," he said.

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