Heterogeneity can predict induction failure in pediatric ALL patients

04/11/2012 | PhysiciansBriefing.com

Children with acute lymphoblastic leukemia who are at risk of induction failure tend to have certain high-risk features, a German study found. Risk factors for induction failure are older age, high leukocyte count, 11q23 rearrangement, T-cell phenotype and Philadephia chromosome, the researchers report in the New England Journal of Medicine. Allogeneic stem-cell transplantation from matched, related donors improved survival in patients with T-cell leukemia, while chemotherapy alone improved survival in children younger than 6 years with precursor B-cell leukemia and no adverse genetic features, the researchers found.

View Full Article in:

PhysiciansBriefing.com

Published in Brief:

SmartBrief Job Listings for Health Care

Job Title Company Location
Eastern Zone Sales Director
Regenesis Biomedical
Multiple Locations, SL_Multiple Locations
Director, Compliance - Health Plan Privacy & Security
Kaiser Permanente
Oakland, CA
Regulatory Counsel
Food and Drug Administration
Silver Spring, MD
Pharmacy Care Manager
National Association of Chain Drug Stores
Arlington, VA
Vice President, Commercial Markets
Meridian Health
Neptune, NJ