A team at Massachusetts General Hospital bioengineered rat kidneys in the laboratory by stripping cells from the organs and placing new tissue-producing cells on the collagen scaffolds. The engineered organs made urine in the lab and after being transplanted into rats, according to the study in the journal Nature Medicine. Bleeding and clotting were not observed following transplantation, but the new kidneys did not work as well as the originals, a researcher said. Using a natural scaffold could have advantages over other methods, the lead investigator said.
Bioengineered kidneys could lead to creation of replacement organs
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