PiB-PET used to explore brain changes

05/29/2013 | MedPage Today (free registration)

Buildup of beta-amyloid in the brain as measured through PiB-PET imaging appears to be linked to memory impairment and gray matter atrophy in cognitively normal adults, according to a subanalysis of the Australian Imaging, Biomarkers and Lifestyle Study of Aging published in JAMA Neurology. The results indicate PiB-PET imaging can be used to identify patients with cognitive impairment, according to the authors. "These findings support the notion that amyloid deposition is not a benign process and that interventions with anti-amyloid therapy at these early stages have a higher chance to be effective," researchers said.

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