Insulin-resistant patients showed lower-than-normal dopamine release in response to glucose compared with healthier controls, a study presented at the SNMMI Annual Meeting indicated. "We suggest that insulin resistance and its association with less dopamine release in a central brain reward region might promote overeating to compensate for this deficit," said lead researcher Dr. Gene-Jack Wang of Stony Brook University in New York. Researchers used PET to monitor the brains of 10 healthy patients and nine patients with insulin resistance.
Study links insulin resistance to lower dopamine release
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