Biomarker allows for cost-effective throat cancer imaging, study suggests

07/25/2013 | Medscape (free registration)

A study published in the Journal of Clinical Oncology found risk stratification using plasma Epstein-Barr virus DNA levels helps determine the utility of PET/CT for finding metastases in nasopharyngeal carcinoma. Chinese researchers conducted PET/CT imaging plus MRI and a clinical workup with chest X-ray, abdominal ultrasound and skeletal scintigraphy in 583  patients. After the evaluation of findings, researchers recommended only clinical workup for very low-risk patients, a choice between clinical workup or imaging for low-risk patients and PET/CT for intermediate-risk patients. PET/CT led to a change in treatment plans for 16.5% of the intermediate-risk patients.

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