Scientists at the University of Cambridge's Department of Veterinary Medicine have shed new light on the mechanism behind human allergic reactions to cat dander, and this report explores the findings in detail. Fel D1, a cat dander protein, becomes allergenic when it combines with bacterial lipopolysaccharide, and together they stimulate a receptor known to cause other types of allergic reactions. Medications that inhibit the receptor already exist, so the scientists think their finding may lead to a cure for people with cat allergies. Dog dander combined with LPS also stimulated the receptor, and people with dog allergies could also benefit from the research.
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