Genetic marker may predict need for aggressive ALL treatment in children

09/5/2013 | Oncology Nurse Advisor online

The presence of four or more copies of the gene RUNX1 in an abnormal chromosome 21 among children with acute lymphoblastic leukemia was associated with poor outcomes, according to a study in the Journal of Clinical Oncology. This gene amplification "helps identify patients who need more therapy than they may otherwise get," study author Dr. Stephen Hunger said.

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