Research explores role of mutations in Alzheimer's

09/26/2013 | MedicalXpress.com

A study in the journal Neuron pinpointed two rare genetic mutations that apparently stimulate buildup of beta amyloid, which is linked to Alzheimer's disease. Using strains of transgenic mice, researchers located the mutations in the ADAM10 gene, which codes for generation of an enzyme that plays a role in processing the precursor to amyloid. They also found that diminished activity of ADAM10 hinders the generation of new hippocampus neurons.

View Full Article in:

MedicalXpress.com

Published in Brief:

SmartBrief Job Listings for Health Care

Job Title Company Location
Attorney
U.S. DEPARTMENT OF HEALTH & HUMAN SERVICES Food and Drug Administration Office of the Chief Counsel
Silver Spring, MD, MD
Counsel – Regulatory Affairs
RAI Services Company
Winston Salem, NC
Senior Manager, Clinical Affairs - Advanced Technology
Edwards Lifesciences
Irvine, CA
Director, Litigation & Investigations EMEA
Gilead Sciences
Stockely Park
Assistant General Counsel/Senior Corporate Counsel
Genentech
South San Francisco, CA