Canine pathogen may be new vector for human vaccines

11/28/2012 | RedOrbit

Researchers at the University of Georgia's College of Veterinary Medicine found that canine parainfluenza virus 5, which doesn't cause disease in humans, can be loaded with antigens from other pathogens and used in a vaccine to generate immunity to those pathogens. Tests in mice have already shown that a PIV5-based vaccine protected them from seasonal flu strains as well as H5N1, or avian influenza. It's possible that the PIV5 vaccines could be used to develop vaccines for HIV, malaria and tuberculosis, according to lead researcher Biao He.

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