A study in The Lancet found that body mass index can be used to help determine the best hypertension drugs for individuals. A diuretic drug worked best in obese patients and was associated with an increased risk of cardiac events in those with normal body weight. A calcium channel blocker worked well in patients who were obese, overweight and lean. The drugs were tested with an ACE inhibitor in the Avoiding Cardiovascular Events in Combination Therapy in Patients Living with Systolic Hypertension study.
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