A review in the Journal of the American Geriatrics Society, based on four studies with 5,789 older adults, found adherence to a Mediterranean diet was linked to a reduced risk of incident frailty. Researchers called for additional studies to confirm the results.
About 43,000 patients at Coplin Health Systems in Elizabeth, W.Va., are being notified that their personal information may be compromised after a hospital laptop was stolen from an employee's car in November. The computer could contain documents with data such as health information, dates of birth, Social Security numbers, addresses and financial information.
Each five-years-longer duration of diabetes and prediabetes in adulthood was associated with a 1.15 and 1.07 higher hazard ratio, respectively, for the presence of coronary artery calcified plaque in middle age, according to a study in Diabetes Care. Researchers used a cohort of 3,628 white and black adults, ages 18 to 30, and found that diabetes and prediabetes duration correlated with early diastolic relaxation and worse subclinical function, while diabetes duration was associated with a higher diastolic filling pressure.
Medical practices that want to better meet the needs of patients should examine their procedures, writes consultant Owen Dahl, including redundant questions on paperwork, overscheduling, lunchtime availability and proper screening for genuine emergencies. Dahl suggests clinicians evaluate their own visits to medical offices to see what works and what doesn't from the patient perspective.
CDC researchers found that 34.7% of pregnant women prescribed an antibiotic for a urinary tract infection received nitrofurantoin and 7.6% were given trimethoprim-sulfamethoxazole, even though the drugs have been associated with an elevated risk of birth defects when taken during the first trimester. Clinicians said the findings, discussed in the agency's Morbidity and Mortality Weekly Report, suggest health care providers may not all be aware of American College of Obstetricians and Gynecologists guidelines advising use of these antibiotics only as a last resort treatment during early pregnancy.
AstraZeneca's Lynparza, or olaparib, has been approved by the FDA to treat patients with metastatic HER2-negative breast cancer whose malignancy involves mutations in the BRCA1 or BRCA2 genes. The drug, which was previously approved for treatment of advanced ovarian cancer, is the first PARP inhibitor to win FDA approval against breast cancer.
A pair of collaborations was launched by Stanford University spinout Forty Seven to evaluate its drug candidate Hu5F9-G4 in combination with Merck's Bavencio, or avelumab, in patients with ovarian cancer, and Genentech's Tecentriq, or atezolizumab, in patients with acute myeloid leukemia and with urothelial cancer. Values of both deals were not disclosed.
Researchers found that the breakthrough PET radiotracer F-18 3-fluoro-4-aminopyridine, which binds to potassium ion channels, accumulated more in demyelinated areas than in control areas of the brains of rodent models with induced demyelination and in healthy monkeys. The findings in Scientific Reports suggest that PET with F-18 3F4AP can complement MRI data in tracking multiple sclerosis lesions and may help monitor responses to remyelinating therapies as well as identify the extent of myelin sheath disruption that is a factor in other central nervous system disorders, said researcher Brian Popko.
A wide variety of liquid replacement meal options are available, but dietitians say there are pros and cons to using them in nutrition and weight-loss plans. Registered dietitian nutritionist Jessica Crandall said decisions on liquid replacement meals come down to screening clients and patients to determine their needs, and RDN Jacqueline Craig says for some people, the cost of the products can be a factor.
Registered dietitian Kelly Devine Rickert says she helps teens who have body image problems that can be linked to health and nutrition misinformation in the news and on social media. Body image problems in children and teens typically begin at home, however, when adults are concerned about their own body image, Devine Rickert says, making it important for parents to present positive images.
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