Type 2 diabetes patients experienced increases in their 24-hour mean systolic and diastolic blood pressure and mean arterial pressure after six weeks of receiving the glucagon receptor antagonist LY2409021 once daily, compared with those on placebo, according to a study in Diabetes, Obesity and Metabolism. French researchers evaluated 270 patients and also found that those on LY2409021 had reduced A1C levels at week six and small but significant changes in aminotransferase and serum lipid levels.
A study in BMJ Open Diabetes Research & Care showed that individuals recently diagnosed with type 2 diabetes were at a fivefold increased odds of reporting a "poor" quality of life, a modest increase in the risk of experiencing psychological distress and reduced social contacts across four types of social contact than those without diabetes. Researchers used a cohort of 26,344 Australian adults without diabetes at baseline and found that the results persisted after adjusting for age, economic status, household income and marital status.
Researchers found that 56.2% of extremely obese women with cytomegalovirus infection had three or more risk factors for metabolic syndrome and higher levels of HDL cholesterol and lower triglyceride levels, compared with 82.6% of those without CMV infection. The findings in Obesity, based on 2,532 individuals ages between 20 and 49, revealed that 4.9% of normal-weight women with CMV had at least three MetS risk factors, compared with less than 1% of normal-weight women without CMV infection.
Providers were better able to correctly interpret patient directives when they included patient-made videos, compared with having just written documents, researchers reported in the Journal of Patient Safety. A survey with nine scenarios involving critically ill patients who had a Physician Orders for Life-Sustaining Treatment form or living will was sent to physicians, most of whom were not trained in evaluating end-of-life documents.
In a new position statement, the ANA has said that it opposes both capital punishment and nurse participation in capital punishment. "Participation in executions, either directly or indirectly, is viewed as contrary to the fundamental goals and ethical traditions of the nursing profession," according to the statement.
A UK study suggests eating 10 servings of fruit and vegetables daily may reduce the risk of disease and prevent some 7.8 million premature deaths worldwide. The study, published in the International Journal of Epidemiology, linked higher intake, compared with not eating fruits and vegetables at all, to a 24% reduction in the risk of heart disease, a 33% reduced risk of stroke, a 28% lower risk of cardiovascular disease and a 13% lower risk of total cancer.
Researchers at the University of Bath and King's College London found that glycation from high blood sugar caused damage to macrophage migration inhibitory factor enzymes involved in inflammatory response in early-stage Alzheimer's disease and increased as Alzheimer's progressed. The findings in Scientific Reports, based on brain samples from 30 people with and without Alzheimer's, will be key to determining how Alzheimer's progresses and could aid in identifying people at risk for the disease and developing new treatments, said researcher Rob Williams.
Many probiotic supplements sold in retail settings will not significantly improve the diversity or health of gut microbiota or health outcomes, said registered dietitian Tamara Duker Freuman. Most probiotics are not backed by scientific testing, some have false or misleading labels and some may be harmful to health, Freuman said.
March is National Nutrition Month, and the 2017 theme of the campaign created by the Academy of Nutrition and Dietetics is "Put Your Best Fork Forward," writes registered dietitian nutritionist Carol Chappell. Some of the messages the campaign will focus on next month include eating a variety of healthy foods, cooking more at home, portion control and the importance of exercise, Chappell says.
A study in the journal Cancer Epidemiology, Biomarkers & Prevention found every 5 kg/m2 increase in usual adult body mass index was tied to a 9% increase in the risk of multiple myeloma. The findings also showed an association between the same increase in young adult BMI and a 20% higher risk of multiple myeloma.
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