A study in JAMA Internal Medicine found that high levels of breast cancer screening may be associated with overdiagnosis without reducing the rate of breast cancer deaths. Researchers compared data on almost 16 million women living in 547 U.S. counties in 2000 and found that a 10 percentage point increase in breast cancer screenings was linked with a 16% increase in breast cancer diagnoses while having no effect on breast cancer mortality.
The consumption of sugar-sweetened beverages was responsible for an estimated 184,000 deaths worldwide in 2010, 133,000 of which were related to diabetes, according to a study in the journal Circulation. Researchers found that Mexico had the highest mortality rate from sugary drinks, with an estimated 405 deaths per one million adults, followed by the U.S. with an estimated 125 deaths per one million adults.
AstraZeneca and Cephalon have reached settlement deals with the U.S. and state governments for separate lawsuits claiming the companies underpaid rebates for their prescription drugs covered under state Medicaid programs. AstraZeneca will pay $46.5 million, while Teva, which owns Cephalon, will pay $7.5 million to settle the allegations. Among the medications named in the lawsuits are Cephalon's wakefulness drug Provigil and pain treatment Actiq, as well as AstraZeneca's Seroquel antipsychotic and Crestor cholesterol medication.
A report in Applied Clinical Informatics discusses how a team of researchers from the University of Missouri helped enhance the health information exchange capabilities of 16 nursing homes. A $14.8 million CMS grant was used to support the building of integrated systems to exchange health records and patient data with other providers. In the study's next stage, researchers will examine whether the changes lead to better communication about care.
Researchers found a positive association between severe hypoglycemia and the severity of depressive symptoms among Japanese patients with type 2 diabetes. The findings were published in BMJ Open Research & Diabetes Care.
A study found an initial misdiagnosis rate of 31% among 313 pancreatic cancer patients. Patients were most commonly misdiagnosed with gallbladder disease, followed by gastroesophageal reflux disease and peptic ulcer disease. At the annual Digestive Disease Week, researcher and surgical resident Douglas Swords said pancreatic cancer should be considered when patients are referred for cholecystectomies with vague or atypical symptoms.
A list of proposals to boost culture change at HHS and inspire employees to find better ways to perform their jobs was released by Chief Technology Officer Susannah Fox after only a few weeks in her new position. Among her proposals are rewarding managers for driving innovation within their teams, boosting the agency's e-mail and calendar systems to enhance cross-departmental collaboration and partnering with the White House to encourage innovators in the agency.
Researchers followed 529 war-affected children from Sierra Leone, ages 10 to 17, from 2002 to 2008 and found that those with higher levels of internalizing symptoms two years after the end of the conflict had worse post-traumatic stress symptoms and more anti-social behavior four years later. The findings were published in the journal Pediatrics.
A study in the Journal of the American Geriatrics Society found that adults at high risk for cardiovascular disease and type 2 diabetes had significant improvements in their CVD-related risk factors after attending 16 weekly core sessions and six monthly post-core sessions of an adapted Diabetes Prevention Program lifestyle intervention. Researchers also found that patients aged 65 and older were more likely to self-monitor their fat intake, achieve weight loss and physical activity goals, and attend more intervention sessions than those younger than 65.
Several health organizations in Cleveland have collaborated to launch the first Cleveland Medical Hackathon on Sept. 26 and 27. Teams or individuals who want to join the hackathon can submit their applications on the Cleveland MedHack website. The hackathon will focus on how Big Data and innovative solutions can be used to address various challenges in health care.