A German study in Diabetes Care shows empagliflozin is not associated with an increased risk of bone fracture among type 2 diabetes patients, compared with glimepiride or placebo. The findings are based on data from more than 12,620 diabetes patients.
Similar mean A1C reductions occurred among patients with type 2 diabetes and obesity who were assigned to an intermittent-fasting intervention or continuous-energy restriction diet, according to a study in JAMA Network Open. Australian researchers used a cohort of 137 adults and found similar mean weight change between the groups but the between-group difference did not meet the criteria for equivalence.
Researchers polled 2,219 physicians, physician assistants and nurse practitioners in more than 20 medical specialties in the US and found that 20.5% of respondents prefer hospital employment, compared with 32% of those who prefer single-specialty groups/partnerships and 17.4% who prefer a multi-specialty group/partnership. The survey from The Medicus Firm also found that more than 90% of the group's physician placements have been hospital employment opportunities over the last two years due to a higher number of openings than in private practices.
HHS Secretary Alex Azar said President Donald Trump's pressure campaign to bring down drug prices is coming to fruition after five pharmaceutical firms announced they will be freezing drug prices this year and one announced plans to lower some prices. Pfizer, Novartis, Roche, Bayer and Merck KGaA have said they will not implement price hikes for the rest of the year, while US-based Merck said it will be rolling back prices for seven drugs, but critics said these announcements don't line up with Trump's promise that there would be massive, voluntary price cuts.
More health insurers are leveraging patient data to develop more effective population health management programs, and one of them is Magellan Health, which saw significant reductions in the suicide rate among its Medicaid enrollees after it addressed both clinical and nonclinical factors such as poverty, food and housing insecurity, and environmental hazards. A recent Change Healthcare survey showed that 42% of payers are integrating community programs and resources into their population health efforts, while another 34% are combining census, socioeconomic data and clinical data to develop new interventions.
Researchers who analyzed recorded consultations between 112 patients and their doctors found that in 7 out of every 10 cases, physicians interrupted patients as they explained their symptoms within an average 11 seconds. The study, in the Journal of General Internal Medicine, found primary care physicians allowed patients more time to describe their ailments without interruption than specialists.
A wearable sweat-sensing device that measures levels of cortisol, a biomarker for immune function, emotional stress and metabolism, has been developed by a team of researchers from Stanford University. The device detects cortisol by blocking the movement of charged ions through a membrane when cortisol is present, the team reported in Science Advances.
Agios Pharmaceuticals' Tibsovo, or ivosidenib, was approved by the FDA as a treatment for adult patients with relapsed or refractory acute myelogenous leukemia with a susceptible isocitrate dehydrogenase 1 mutation. The company intends to seek European Medicines Agency approval in a filing submitted in the next quarter.
The FDA has approved Pfizer's Nivestym, a biosimilar version of Amgen's Neupogen, or filgrastim, and Pfizer said it will be available in the US for all indications of Neupogen at a significantly lower price than the reference drug. Reduction of infection risk in certain patients with cancer is among the indications.
Kentucky will reinstate dental and vision benefits for nearly 500,000 Medicaid recipients after Gov. Matt Bevin canceled the benefits earlier this month following a court decision to block Medicaid work requirements. Administration officials said they now recognize the work requirements will be delayed and they want to prevent a lengthy coverage gap.
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