Youths whose mothers had greater exposure to p,p'-dichlorodiphenyl dichloroethylene, a metabolite of the banned insecticide dichlorodiphenyltrichloroethane, or DDT, during pregnancy were more likely to develop autism, researchers reported in the American Journal of Psychiatry. No association was found between prenatal exposure to polychlorinated biphenyl, or PCB, pesticides and autism risk.
Patient access to health records remains a challenge, with a survey finding that 63% of Americans are unaware of where their health care data is stored or who has access to it. The CMS has launched the MyHealthEData Initiative for Medicaid and Medicare's EHR programs, and the agency has started using Medicare Blue Button 2.0, a new software protocol for developers.
President Donald Trump urged Attorney General Jeff Sessions to file a lawsuit against certain manufacturers of opioid painkillers and to take action against foreign companies, particularly in China. Trump didn't specify which companies he wants to sue, but a number of states have already filed cases against opioid makers such as Purdue Pharma, alleging they contributed to the opioid abuse crisis.
South Korean researchers who used optical coherence tomography found that drug-naive individuals who have early Parkinson's disease had retinal thinning, which was associated with nigral dopaminergic loss and disease severity. Confirmation of the findings, which were published in Neurology, may prompt the use of retinal scans not only to provide earlier Parkinson's treatment but also to improve monitoring of therapies that may delay disease progression, researcher Dr. Jee-Young Lee said.
A report from the American Cancer Society Cancer Action Network finds that cancer care in California and Massachusetts is the best in the nation, with policies promoting cancer prevention, palliative care, pain management and expanded access to health care. Chris Hansen, CAN president, said establishing and enforcing policies outlined in the report will help stakeholders meet the needs of cancer patients, save lives and reduce long-term health care costs.
PET/MRI with 15-minute pelvic PET acquisitions identified 40% more FDG-avid lymph nodes without extending scan times among individuals with rectal cancer, compared with PET/MRI with three-minute pelvic PET acquisitions, and resulted in the upstaging of more than 64% of patients, according to a study in the American Journal of Roentgenology. The findings should prompt the inclusion of 15-minute PET pelvic acquisitions in pelvic PET/MRI during rectal cancer staging, researchers wrote.
Singaporean researchers found that intensified therapy for pediatric patients with childhood B-cell acute lymphoblastic leukemia and IKZF1 deletion resulted in a reduction of relapse risk and improved overall survival. The findings were published in the Journal of Clinical Oncology.
SPR Therapeutics secured clearance from the FDA for its SPRINT endura (single lead) and extensa (dual lead) Peripheral Nerve Stimulation systems for pain management. The platforms, which are indicated for use in the extremities or the back for up to 60 days to treat acute and chronic pain, enable two leads attached to a wearable pulse generator to be implanted by physicians during an outpatient procedure.
Trovagene announced it has finished dosing the second cohort for its Phase Ib/II trial of its PLK1 inhibitor onvansertib indicated for acute myeloid leukemia. Preliminary efficacy data were encouraging, according to the lead investigator at Yale University.
A study in the American Journal of Roentgenology showed that over 18% of radiologist and trainee groups given visual aids had contrast medium reaction management errors, compared with 40% of groups without visual aids, while mean intramuscular epinephrine administration time was 25 seconds faster among those using visual aids. Over 97% and 87% of participants reported that visual aids would help in administering medication and reducing administration times, respectively.