Mission Hospital in Asheville, N.C., honored tissue donors and transplant recipients by raising a Donate Life flag for Donate Life Month in April. "The gift of eye and tissue donation can save and enhance the lives of 50 people," said Sarah Briggs of Lifeshare of the Carolinas
During April's Donate Life Month, Department of Motor Vehicle offices in New York will educate drivers about the benefits of joining the New York State Donate Life Registry. DMV offices are "where New Yorkers can make the important decision to be a hero to a person in need and give the gift of life," said New York Alliance for Donation Executive Director Aisha Tator.
The CDC has issued a travel notice for areas of South Africa due to an outbreak of malaria. The Waterberg district has been added to areas of Limpopo province where travelers are advised to take antimalarial drugs as a preventive measure. Visitors to the North West and Gauteng provinces are advised to take normal precautions against being bitten by mosquitoes.
Health officials in Zimbabwe have reported almost 90,000 cases of malaria and 150 deaths, due to increased rains and flooding and a lack of access to health care facilities.
The Ebola virus activates macrophages through the Toll-like receptor 4 pathway, leading to excess production of inflammation-promoting cytokines and chemokines, according to a study in the Journal of Virology. Compounds that inhibit the TLR4 protein may lead to new treatments for Ebola, investigators from Boston University School of Medicine said.
Nohla Therapeutics and the University of California at Davis have partnered to produce the drug candidate NLA101, an off-the-shelf universal donor stem and progenitor cell therapy for hematologic cancers. The therapy is currently in a Phase IIb study.
An additional Singapore patent has been secured by Orthocell for its Celgro Smart Graft, a collagen-based medical device designed for use in soft-tissue regeneration. The patent refers to the company's manufacturing method for novel bio-scaffolds that are intended for facilitating surgical treatment of soft-tissue injuries.
All currently marketed laboratory-developed tests, so-called traditional LDTs and tests for public health monitoring should be exempted from FDA oversight, except for reporting adverse events and malfunctions, according to a discussion paper released by the agency. "A prospective oversight framework that focuses on new and significantly modified high- and moderate-risk LDTs would best serve public health and advance laboratory medicine," the agency said.
An infant with a splenic injury and severe hemophilia A, a rare condition for newborns, was successfully treated with multiple blood transfusions and infusions of recombinant factor VIII concentrate without the need for surgical intervention, according to a case study in the journal Hematology Oncology and Stem Cell Therapy. After discharge, the infant "continued to be followed in our comprehensive hemophilia clinic every 6 months," the care team wrote.
Researchers at Emory University found that type A plasma can be used with minimal risk in a massive transfusion protocol for type AB or B trauma patients, though transfusion of more units may be needed. The 1,536-patient study, based on data from eight trauma centers, was presented at a meeting of the Eastern Association for the Surgery of Trauma.
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