Washington University in St. Louis researchers developed a diagnostic test for the Zika virus that uses gold nanorods on paper that change color if the blood sample contains the pathogen, also yielding results in minutes, according to a study published in the journal Advanced Biosystems. No false-positive results were generated when the investigators tested the assay on four people infected with Zika compared with blood samples from five uninfected people.
The glycan binding protein Y3 found in the Coprinus comatus mushroom, more commonly known as "shaggy ink cap," was discovered by University of Florida researchers to be associated with activating a cell-signaling cascade that programs a specific leukemia T cell type to kill itself, according to the journal Proceedings of the National Academy of Sciences. The study suggests the use of this protein could affect potential new therapies for patients with acute lymphoblastic leukemia.
Only 135 cases of Zika virus infection have been reported in Florida as of August 10, with all but one case travel-related, compared with 470 Zika cases reported in the state during the same period in 2016. Experts attribute the decline to more aggressive mosquito control initiatives and a decrease in Zika infections in South America and the Caribbean.
A study in the Journal of Clinical and Experimental Hepatology found that 96% of 25 elderly patients with hepatitis C virus infections responded to sofosbuvir-based treatments. The patients ranged in age from 70 to 81.
President Donald Trump on Thursday declared the opioid abuse epidemic a national public health emergency as recommended by the White House's opioid commission, two days after administration officials said the move was not necessary. Six states have already declared statewide emergencies, a move that has allowed them to negotiate improved access to naloxone, an opioid overdose reversal medication.
A worldwide survey presented at the 2017 World Indigenous Peoples' Conference on Viral Hepatitis found that indigenous peoples in the Americas, Australia and New Zealand had higher rates of hepatitis B and hepatitis C infection than the general population. Causes can include poverty and a lack of access to health care.
Baylor College of Medicine researchers are developing virus-specific cells -- including for the Epstein-Barr virus, adenoviruses, cytomegalovirus, BK virus and human herpesvirus 6 -- to treat viral infections in patients who receive hematopoietic stem cell transplants, according to a study in the Journal of Clinical Oncology. Thirty-eight patients received a single infusion, and the overall complete or partial response rate was 92%.
The results of a study being published in the New England Journal of Medicine are favorable toward a blood test that helps doctors detect a particular type of cancer -- a good sign for biotech startup Grail as it further develops the test. The startup's investors include pharmaceutical company Merck and China's Tencent, as well as Bill Gates and Jeff Bezos.
Kite Pharma filed an investigational new drug application for its chimeric antigen receptor T-cell therapy, KITE-585. Kite intends to launch an early-stage, first-in-human trial to assess the efficacy of its targeting B-cell maturation antigens in patients diagnosed with relapsed or refractory multiple myeloma.
University of Arizona public health researchers developed the Kidenga mobile application to allow people to anonymously report symptoms of possible Zika virus infection. The app is intended to allow the early identification of clusters of illnesses that could be Zika, dengue or chikungunya.