Fate Therapeutics and the University of California at San Diego entered an agreement to develop chimeric antigen receptor-targeted natural killer cell cancer immunotherapies. Financial details of the deal were not disclosed.
The Journal of the American College of Cardiology published new guidance from the American College of Cardiology on the management of patients who experience bleeding while taking anticoagulants. Risks and benefits, as well as the initial indications for starting anticoagulation, should be reconsidered before restarting the drugs, according to the guidance.
The World Health Organization's International Coordinating Group has given 1.4 million vaccines to Nigeria to stem the spread of yellow fever. An outbreak of yellow fever started in August and has increased to 30 confirmed cases and 276 suspected cases.
Bio-Manguinhos, a subsidiary of Brazil's Oswaldo Cruz Foundation, entered into a deal with Chembio Diagnostics to purchase $8.5 million worth of test components and intermediate product for the production of Chembio's DPP HIV and Leishmania assays. The companies expect the sales to occur next year.
European regulators gave Bio-Rad Laboratories CE-IVD marking for its QXDx BCR-ABL %IS Kit, a droplet digital PCR assay intended for the detection of BCR-ABL gene fusions. The test, which provides absolute quantification and scalable throughput from eight to 48 samples per run, can facilitate monitoring of response to treatment in chronic myeloid leukemia patients.
The rise in rates of methicillin-susceptible Staphylococcus aureus, as well as resistance to antibiotics such as clindamycin and Bactrim, underscore the importance of understanding antimicrobial resistance when prescribing antibiotics, according to research presented at the Infectious Diseases in Children Symposium. A study by the Vanderbilt Vaccine Research Program found that using Bactrim to treat pediatric patients who had undergone drainage procedures due to MRSA infections resulted in a 25% increased risk of recurrence and an almost doubled risk of treatment failure.
Ashley Power said "it really wasn't a decision" when she was presented with a choice of whether to donate her son Jake's corneas after his death in an accident in 2013 because he was such a giving child. John Martinez of SightLife works with grieving families and says it's not uncommon for them to not know about the option of cornea donation.
The American Association of Tissue Banks will sponsor the presence of 17-year old tissue recipient, Peter "P.J." Williams, on the Donate Life Rose Parade float on Jan. 1. P.J. was diagnosed with bone cancer when he was 12 but was able to overcome his disease and maintain normal growth and mobility thanks to a donated gift of musculoskeletal tissue. The stories of young people will be among those highlighted on this year's float, whose theme is "Gift of Time."
Nonprofit organ procurement organizations, which match patients across the nation with donated tissue and organs, are using business intelligence and analytics tools to improve community outreach and monitoring of their metrics. "In donation and transplant, there isn't any room for error. You can imagine that if you or a loved one was in need of a lifesaving organ, it would not be acceptable for us to make a mistake," Indiana Donor Network Chief Operating Officer Steve Johnson said.
Donated corneas can be stored safely for 11 days before surgery, according to a study in JAMA Ophthalmology based on data for 1,090 Descemet stripping automated endothelial keratoplasty procedures. Rates of graft success after three years were similar for tissue stored up to a week and for tissue stored eight to 14 days.