The Susan G. Komen Tissue Bank will hold a healthy breast tissue collection event in March at Banner MD Anderson Cancer Center in Gilbert, Ariz. "By donating normal breast tissue, a woman can help scientists understand more about breast cancer. We believe that this is a truly genuine and personal way for women to contribute to breast cancer research," Dr. Lida Mina said.
NIH researchers ended a clinical trial after healthy volunteers taking a combination of the HIV drug dolutegravir and the tuberculosis treatment isoniazid-rifapentine had "unexpected and serious toxicities," according to a report in the journal Clinical Infectious Diseases. Two of four participants developed influenza-like syndrome and one was hospitalized for a day, and researchers said the drugs should be combined "cautiously, ideally in a clinical research setting."
The American College of Surgeons is calling for teachers to receive "Stop the Bleed" training and for school systems to put stop-bleeding kits in every classroom. Training in basic bleeding-control techniques can save lives, said Dr. Jeff Kerby of the University of Alabama at Birmingham School of Medicine.
The Global Commission to End the Diagnostic Odyssey for Children, formed by Shire, Microsoft and EURODIS Rare Diseases Europe, will form a multidisciplinary group of experts with the goal of expediting the diagnosis of children with rare diseases. "We're seeking innovative ways to integrate emerging technologies into our efforts, which will play a critical role as we strive to impact the diagnosis journey," said Microsoft Chief Medical Officer and Senior Director Dr. Simon Kos.
Celularity, a stem cell startup that collects placenta stem cells for health care products, has raised $250 million. The company is selling wound-healing products and developing immunotherapies.
Anthropology professor Trudy Turner's study of monkeys began with population genetics studies that led to a larger study of simian immunodeficiency virus, which is similar to HIV but does not cause similarly devastating symptoms. Researchers have build a substantial biobank, and the international study might lead to insights about HIV as well as other diseases that affect human and nonhuman primates.
Veterinarians, scientists, communications staff and lab administrators from North America and Europe explored ways to build public trust in animal research at the recent Basel Declaration Society conference, discussing the importance of nonhuman primates in neurology research, myths about animal research and more. FBR President Matthew R. Bailey spoke at the event, noting a shift in animal rights activism "from extreme activities to public policy activities." Bailey urged the research community to "stop operating based on fear" and embrace transparency and openness around their work.
Scientists have created a second successful human-animal hybrid embryo comprising 99.99% sheep cells and 0.01% human cells by count, moving scientists one step closer to being able to grow human organs in animals for transplant. Only about 2,000 people in the US get heart transplants each year out of more than 100,000 Americans who need them, and 22 people on the US organ transplant list die each day.
Cloning had become somewhat normalized in the two decades since Dolly the sheep was cloned from an adult sheep's mammary gland cell, but news that scientists in China had cloned two monkeys renewed debate on the ethics of cloning. The scientists in China say that cloned nonhuman primates can advance research, but cloning is most likely to be used in the future to produce better livestock, says cloning expert Robin Lovell-Badge.
FDA Commissioner Scott Gottlieb said the agency is taking steps to prevent the potential misuse and abuse of gabapentinoids, which could result in serious adverse events. The agency was alarmed by reports of off-label prescribing of gabapentinoids to treat pain, and as an alternative to opioids.