Dermatologists often see elderly patients complaining of total body itch that has no clear cause. Total body itch can be caused by excessively dry skin, pests, allergies, drug reactions or underlying disease, such as hypothyroidism, anemia or lymphoma, said dermatologist Dr. Joseph Bikowski. If no cause can be identified via a thorough work-up, doctors can try to treat the itch with fexofenadine, a nonsedative antihistamine, or prednisone.

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