10/11/2011

PET with carbon-11-labeled Pittsburgh Compound B showed that treatment with an antibody called gantenerumab can reduce the levels of amyloid-beta plaque in the brains of patients with Alzheimer's disease, according to a Swiss study published in the Archives of Neurology. The reduction in the plaque was directly related to the size of the treatment dose, the researchers said. "Additionally, our findings in the placebo-treated patients support previous reports indicating that amyloid load continues to increase in many patients with mild-to-moderate Alzheimer's disease," the researchers added.

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