Using an intra-arterial catheter that combines both optical frequency-domain imaging and near-infrared fluorescence imaging helped identify fibrin on implanted stents in areas in living rabbits undetected by OFDI alone, according to a study published in Nature Medicine. The combined method also detected atherosclerotic plaques and enzymatic activity related to inflammation and plaque rupture. "If OFDI-NIRF is validated in clinical studies, patients at risk for stent thrombosis could undergo a 'stent checkup' to determine how well the stent is healing," said researcher Dr. Farouc Jaffer.

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