Two experimental drug combinations extended survival in women with advanced breast cancer, according to studies presented at the San Antonio Breast Cancer Symposium and published in The New England Journal of Medicine. In one study, women with HER2-positive breast cancer treated with Genentech's Herceptin, chemotherapy and experimental drug pertuzumab lived an average of 18.5 months without recurrence, compared with 12.4 months in the group receiving only Herceptin and chemotherapy. Genentech applied for FDA approval of pertuzumab this week.

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