Changes in fingernails can be signs of serious underlying health problems, such as skin cancer, renal disease, anemia and respiratory infections, says Mayo Clinic dermatologist Dawn Davis. Clubbing, sloping, splitting, yellowing or streaking of the nails are among the warning signs, she says. "If your nails change or start to look abnormal, talk to your doctor or a dermatologist to investigate the underlying cause to see if any treatment is needed," she writes.

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