A study in The Journal of Clinical Endocrinology & Metabolism showed that endothelial dysfunction, as assessed by flow-mediated dilation, may strongly predict diabetic peripheral neuropathy. Researchers found that endothelial dysfunction also mediates the harmful effects of diabetes on the risks of DPN and cardiovascular disease.
Inhibiting vitamin A metabolism helped white fat cells attain characteristics similar to calorie-burning brown fat, researchers reported in Nature Medicine. The findings may aid in the discovery of new treatments for obesity.
Researchers at Rockefeller University in New York stimulated insulin production in mice by injecting iron oxide nanoparticles coated with antibodies into tumors under the animals' skins and then using radio waves to manipulate the particles to generate heat. The results were published in Science.
Cornell University researchers found that women in their third trimester of pregnancy who consumed 930 milligrams of choline daily had babies with a 33% lower cortisol concentration than those who consumed 430 milligrams. Extra choline consumption during pregnancy could lower the child's odds of developing stress-related conditions such as type 2 diabetes and hypertension into adulthood, one researcher said. The findings appear in The Journal of the Federation of American Societies for Experimental Biology.
NeuroMetrix has partnered with Nipro to sell its NC-stat blood test designed to diagnose diabetic peripheral neuropathy. The firms plan to unveil the point-of-care test at the American Diabetes Association's annual conference later this month.