A study in The Journal of Clinical Endocrinology & Metabolism showed that endothelial dysfunction, as assessed by flow-mediated dilation, may strongly predict diabetic peripheral neuropathy. Researchers found that endothelial dysfunction also mediates the harmful effects of diabetes on the risks of DPN and cardiovascular disease.
Eli Lilly and Co. spent $248.7 million advertising erectile-dysfunction drug Cialis to consumers last year to lead a list of the most-advertised branded prescription drugs, followed by Pfizer's $228.9 million in spending on ads for the fibromyalgia and diabetic neuropathy drug Lyrica. Overall, Pfizer spent about $1 billion on its drugs in the top 10, and the industry spent $3.4 billion, according to Nielsen.
A new study in the journal Diabetes Care using ultrasound has found that decompression of the tibial nerve did not reduce its cross-sectional area in patients with painful diabetic peripheral neuropathy. "We're not suggesting that decompression isn't worthwhile, only that we didn't find an effect of surgery on CSA using ultrasound," said study coauthor Marita Schouten. The authors plan a second paper on clinical outcomes such as relief from pain and tingling.
A study presented at the American Association of Clinical Endocrinologists annual meeting found diabetes patients with neuropathy showed worse electrochemical skin conductance, as measured by the FDA-approved Sudoscan test, than those who did not have neuropathy. Researchers said the test may be useful for early diagnosis of diabetic neuropathy and for evaluation of responses to therapeutic interventions.
NeuroMetrix has partnered with Nipro to sell its NC-stat blood test designed to diagnose diabetic peripheral neuropathy. The firms plan to unveil the point-of-care test at the American Diabetes Association's annual conference later this month.