Pfizer's Lipitor, or atorvastatin, topped Genetic Engineering & Biotechnology News' list of best-selling drugs between 2000 and 2011 based on publicly available sales figures. Lipitor generated sales of $121.4 billion during the period. Bristol-Myers Squibb and Sanofi's Plavix, or clopidogrel, came in second with $74.6 billion, followed by GlaxoSmithKline's Advair with $58.8 billion. Rounding out the top 10 were Eli Lilly and Co.'s Zyprexa, Amgen's Enbrel, AstraZeneca's Nexium, Merck & Co.'s Singulair, AstraZeneca's Seroquel, Sanofi's Lovenox and Abbott Laboratories' Humira.

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