Data from an Australian study indicate that patients with Alzheimer's disease have abnormalities in retinal vascular parameters, such as a higher arteriole-to-venule ratio and narrower veins, according to a study published in Translational Psychiatry. PiB-PET imaging also showed that people without the disease who had high levels of neocortical plaque accumulation also manifest some RVP changes, suggesting they may have preclinical Alzheimer's. Eye tests may present another option for diagnosing Alzheimer's, although not as a stand-alone method, researchers said.

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