A project to map the workings of the human brain will cost more than $3 billion, according to some estimates, but the return on investment is potentially significant, project founders say. New tools and collaborative efforts will be needed to measure brain activity in new ways and to visualize the full spatial extent of neurons in the human brain, experts say. "This effort will be both the stimulus and the challenge to work and collaborate in ways we haven't done before, but always have wanted to," said John Mazziotta, director of the Brain Mapping Center at the University of California, Los Angeles.

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