A combination of neuropsychological and physical assessments to determine stroke risk plus PET imaging with FDDNP to measure accumulation of amyloid beta plaques and neurofibrillary tau tangles in the brain may improve early diagnosis of cognitive decline, according to a study published in the Journal of Alzheimer's Disease. Researchers said higher stroke risk was associated with poorer cognitive performance and that study participants who demonstrated greater difficulty with cognitive tasks had higher uptake of FDDNP in areas of the brain that govern such activity. "The findings reinforce the importance of managing stroke risk factors to prevent cognitive decline," said researcher David Merrill.

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