It's natural to feel a sense of rejection if recipients don't respond to your e-mails, but the real reasons for the silence can be more nuanced. Recipients may be buried under a mountain of other messages, they may be unsure of how to say "no" to your request or they may have intended to write a lengthy reply and simply forgotten. If a lack of responses is driving you crazy, it may be time to pick up the phone to resolve the issue.

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