A study in The Journal of Urology found undergoing thiazide diuretic prophylaxis for kidney stones does not raise the odds of diabetes onset in patients. "Larger studies are needed to determine if there is a modest risk of diabetes mellitus with thiazide diuretics," researchers said.
The FDA approved Oramed Pharmaceuticals' investigational new drug application for ORMD-0801, an oral insulin capsule for patients with diabetes. The company plans to begin a Phase II clinical trial of the drug for type 2 diabetes in the U.S.
Data on 559 teens ages 14 to 18 showed those who had a low-fiber diet had bigger waistlines and greater levels of inflammatory factors in the blood, increasing their risk of diabetes and cardiovascular disease. The findings appear in the Journal of Clinical Endocrinology and Metabolism.
A study in JAMA found that daily low-dose aspirin intake was linked to a higher risk of major cerebral or gastrointestinal bleeding and that diabetes patients had a 36% increased risk of bleeding, regardless of aspirin use. "Our study shows, for the first time to our knowledge, that aspirin therapy only marginally increases the risk of bleeding in individuals with diabetes. These results can represent indirect evidence that the efficacy of aspirin in suppressing platelet function is reduced in this population," researchers said.
Low-dose oral contraceptives double the risk for heart attack or stroke among women and may be a danger for women taking the pill longterm or those with other risk factors, according to a Virginia Commonwealth University study. The findings, published in the July issue of the Journal of Clinical Endocrinology and Metabolism, says the risk seems to dissipate after women stop taking the pill.