A study in The Journal of Urology found undergoing thiazide diuretic prophylaxis for kidney stones does not raise the odds of diabetes onset in patients. "Larger studies are needed to determine if there is a modest risk of diabetes mellitus with thiazide diuretics," researchers said.
The FDA approved Oramed Pharmaceuticals' investigational new drug application for ORMD-0801, an oral insulin capsule for patients with diabetes. The company plans to begin a Phase II clinical trial of the drug for type 2 diabetes in the U.S.
Data on 559 teens ages 14 to 18 showed those who had a low-fiber diet had bigger waistlines and greater levels of inflammatory factors in the blood, increasing their risk of diabetes and cardiovascular disease. The findings appear in the Journal of Clinical Endocrinology and Metabolism.
A study in Diabetes Care revealed that women without gestational diabetes mellitus who have a large-for-gestational-age delivery showed no signs of metabolic dysfunction as generally seen in those with the disease. Researchers studied women with nonGDM-LGA, women with GDM and women without either condition and found that those with gestational diabetes had higher fasting glucose levels and lower mean adjusted insulin sensitivity and beta-cell function than women in the other groups.
Low-dose oral contraceptives double the risk for heart attack or stroke among women and may be a danger for women taking the pill longterm or those with other risk factors, according to a Virginia Commonwealth University study. The findings, published in the July issue of the Journal of Clinical Endocrinology and Metabolism, says the risk seems to dissipate after women stop taking the pill.