The number of emergency department visits linked to Ambien and other zolpidem-based sleep medications increased from around 6,000 in 2005 to more than 19,000 in 2010, with women more often affected than men, researchers from the U.S. Substance Abuse and Mental Health Services Administration found. Total cases of adverse reactions to zolpidem jumped nearly 220% between 2005 and 2010, according to the report.

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