Patients with arterial disease plus low baseline diastolic blood pressure showed greater progression of subcortical atrophy at 3.9 years compared with those who had higher baseline blood pressure that declined over time, new research indicates. "This could imply that blood pressure lowering is beneficial in patients with higher blood pressure levels, but caution should be taken with further blood pressure lowering in patients who already have a low diastolic blood pressure," researchers wrote in JAMA Neurology.

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