Previously untreated type 2 diabetes patients who either took empagliflozin or sitagliptin showed greater improvements in A1C compared with a placebo group, according to a study in The Lancet Diabetes & Endocrinology. Patients in the empagliflozin arm also showed better fasting plasma glucose and greater reductions in weight, waist size and systolic blood pressure compared with the sitagliptin group, suggesting the drug is effective as monotherapy.

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