Contact with horses can be as soothing for equine veterinarians as anyone else, but a career in equine veterinary medicine is also physically demanding and highly stressful with long, unpredictable work hours, high student debt loads, administrative burdens and emotional stressors. Equine veterinarians may also be subject to isolation, unrealistic client expectations and demands, and harassment, says AVMA Director of Wellbeing and Diversity Initiatives Dr. Jen Brandt, who helped start a veterinary mental health group with counselors and social workers who specialize in veterinary medicine.
Researchers evaluated data from the EXSCEL study involving 10,782 participants with type 2 diabetes and cardiovascular disease and found that those who received exenatide 2 mg injection once a week had a 10% relative risk reduction for major adverse CV events, such as CV death, nonfatal stroke and nonfatal myocardial infarction, compared with those on placebo. The findings, presented at the Heart in Diabetes conference and published in Circulation, also showed that all-cause mortality rate was lower in the exenatide group.
Researchers used a cohort of 253 young adults, ages 10 to 20, and found that those with Down syndrome had an increased risk of developing prediabetes and dyslipidemia, compared with those without the condition. Findings in the journal Pediatrics also showed that youths with DS had significantly higher levels of triglycerides, LDL cholesterol and non-HDL cholesterol and lower levels of HDL-C, as well as less lean mass for BMI z score, fat mass and visceral fat, but higher visceral fat at higher fat mass.
Findings published in the Journal of Diabetes and its Complications found that 77.3% of 4,398 adults with type 2 diabetes had a serum magnesium level of at least 0.74 mmol/L after taking 10 mg of dapagliflozin daily for 24 weeks, compared with 29.5% of those in the placebo group. The analysis also showed that SGLT2 inhibitor treatment more effectively reduced blood pressure and heart rate measures than placebo.
UnitedHealth Group's Optum, which had been purchasing physician practices and health care facilities, has launched a new business model aimed at taking over certain nonclinical operations for health systems, including purchasing, information technology and revenue cycle management. It has a deal with John Muir Health in San Francisco, and OptumInsight CEO Eric Murphy said its analysis suggests a potential market of several hundred regional health systems.
Chinese researchers found that a deep-learning model, which analyzed PET and MRI scans, along with cognitive impairment test scores, yielded 96.6% sensitivity, 95.4% specificity and 98.5% accuracy in differentiating individuals with normal cognition from those with Alzheimer's disease. The model, described in the journal Neurocomputing, also had 90.1% sensitivity, 91.8% specificity and 85.7% accuracy in distinguishing those who were cognitively normal from those with mild cognitive impairment, as well as 97.4% sensitivity, 84.3% specificity and 88.2% accuracy in differentiating between those with MCI and those with Alzheimer's.
An agreement has been made between Interpace Diagnostics and the Helomics division of Predictive Oncology for the development of products that will diagnose and assess the risk of thyroid cancer. Under the deal, Interpace's existing clinical data will be used to make a model to identify druggable targets in the treatment of indolent and aggressive thyroid cancers.
Moleculin Biotech announced that dosing for its Phase I/II study being conducted in Poland to assess the efficacy of annamycin in relapsed or refractory acute myeloid leukemia will advance to the next dose level of 180 mg/m2 since no adverse events related to the drug were experienced by participants who received the lower dose of 150 mg/m2. A parallel study is also being conducted by Moleculin in the US.
Being in a healthy relationship means partners can respectfully discuss issues and communicate without blame, says Colleen Clark Lay, a licensed clinical social worker. Conflicts that include "name-calling, physical threats against one's self or their partner and threats to end the relationship with no intent to follow through," may indicate attempts to gain power and control that are sometimes connected with domestic abuse.
Louisiana has the most idle and socially disconnected youth ages 16 to 24 -- those not going to school or working -- among all states and Washington, D.C., this analysis finds. These are some of the major challenges at-risk youth face, and licensed master social worker Ashley Palmer says reducing such disconnection means also addressing other issues such as internet access, housing affordability and transportation.
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