Researchers from Australia's Burnet Institute captured video of a malaria parasite blocked from entering a red blood cell after it was treated with two antibodies, according to a study in the journal Cell. In laboratory tests, one antibody from an RH5 protein vaccine slowed the parasite's ability to enter red blood cells, while another antibody attached itself to the parasite, blocking its ability to infect the cells.
Increases in the number of Ebola virus infections in the Democratic Republic of Congo as well as the introduction of cases in Uganda have prompted the World Health Organization to declare an international health emergency. "There is a very real risk that the Ebola outbreak could spread to neighboring countries, so the international community should urgently come together to make sure that doesn't happen," UNICEF Executive Director Henrietta Fore said.
In the Philippines, 456 people have died from dengue this year, with more than 100,000 dengue cases reported in the first half of the year, an 85% increase in cases over the same period in 2018. A national dengue alert has been declared by health authorities.
Kephera Diagnostics has been awarded an NIH grant worth $594,008 to develop a test for determining the effectiveness of Chagas' disease therapies.
Regulation of stem cell treatments has been tightened by the Therapeutic Goods Administration of Australia to protect consumers against unproven products. All manufacturers of cell and tissue products who do not operate within a hospital must satisfy the TGA's requirements for effectiveness, quality and safety, with those failing to comply liable for criminal charges.
Patients diagnosed with hematological malignancies were commonly found to have symptoms of depression, which was linked to shorter survival. Findings from the 255-patient study were reported online in the journal Psycho-Oncology.
Agilent Technologies said it plans to acquire BioTek Instruments, which specializes in the design, production and distribution of life science instruments, for $1.165 billion. The deal "will really solidify our position in cell analysis, and particularly in the spaces of immuno-oncology and immunotherapy overall," said Jacob Thaysen, president of Agilent's Life Sciences and Applied Markets Group.
A Series A funding round has pulled in $17.1 million for Cradle Genomics, a startup developing non-invasive prenatal tests. The company plans to use the money to fund CLIA lab operations, corporate infrastructure, and clinical development and commercial launch of its prenatal tests.
The CDC is focusing on 50 communities in an effort to prevent and treat HIV/AIDS, and CDC Director Dr. Robert Redfield visited Houston to discuss the agency's goal of decreasing new cases by 75% in the next five years and by 90% by 2030. "I always say this initiative is not a Washington-driven initiative. It will be locally defined by your health department and your community here and it needs to be by the community, for the community, in the community," Redfield said.
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